We have 233 MRC PhD Projects, Programmes & Scholarships

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MRC PhD Projects, Programmes & Scholarships

We have 233 MRC PhD Projects, Programmes & Scholarships

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(MRC NW-DMS) Discovering Early Mitochondrial Failure Signatures in Metabolic Disease across the Cardio-Renal Axis

The University of Manchester
Division of Cardiovascular Sciences
  Research Group: Division of Cardiovascular Sciences
Type 2 diabetes affects hundreds of millions of people worldwide and is a major driver of both heart failure and chronic kidney disease. Read more
 Supervisors: Dr A Kitmitto, Dr AL Lay, Prof E Cartwright
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Reliable Multimodal Agentic AI for Cardiovascular Disease Diagnosis and Risk Prediction

The University of Manchester
Division of Informatics, Imaging and Data Sciences
  Research Group: Division of Informatics, Imaging and Data Sciences
Diagnosing cardiovascular disease and predicting future health risks require doctors to combine heart scans, electrocardiograms (ECGs), blood tests and medical records. Read more
 Supervisors: Dr J Duan, Prof S Ananiadou, Dr Chris Miller
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Mapping immune and microbiome crosstalk in Cutaneous Crohn’s Disease

The University of Manchester
Division of Immunology, Immunity to Infection and Respiratory Medicine
Crohn’s disease (CD) is an autoimmune inflammatory bowel disease characterised by severe inflammation in response to resident gut bacteria. Read more
 Supervisors: Prof S Cruickshank, Dr K Coyte, Dr K Couper, Dr LH Hancock
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Bacterial anti-phage defence systems as determinants of phage therapy and host immunity during respiratory infection

The University of Manchester
Division of Immunology, Immunity to Infection and Respiratory Medicine
  Research Group: Division of Immunology, Immunity to Infection and Respiratory Medicine
Bacteriophages are viruses that infect bacteria and are being investigated as a promising alternative to antibiotics. However, bacteria carry specialised anti-phage defence systems that can block phage infection, and we still know little about how these defences influence phage therapy inside a living host. Read more
 Supervisors: Dr S Federici, Prof J Allen
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Examining the interplay between subjective sleep quality, interpersonal relationships, and suicidal experiences in young people with mental health problems

The University of Manchester
Division of Psychology and Mental Health
Suicide is a leading cause of preventable death. Suicidal thoughts and attempts occur even more frequently, particularly in young people with mental health problems (Butt et al., 2025; Ghizlane et al., 2026). Read more
 Supervisors: Dr KH Harris, Dr L.M Mulligan, Dr P Gooding
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Mapping how memory T cell responses develop and are maintained in tissue environments following infection

The University of Manchester
Division of Immunology, Immunity to Infection and Respiratory Medicine
  Research Group: Division of Immunology, Immunity to Infection and Respiratory Medicine
Whilst much of immunological research involves disaggregating tissues into single-cell suspensions so that high parameter cell phenotyping can be performed accurately, this approach completely removes tissue context and information on where a cell is, what it interacts with, and how it is shaped by and shapes its local environment is lost. Read more
 Supervisors: Dr K Couper, Dr DD Dyer, Prof N Lockyer
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Investigating the effects of prenatal exposure to anti-seizure medications on circadian system development and function later in life

The University of Manchester
Division of Integrative Physiology
  Research Group: Division of Diabetes, Endocrinology and Gastroenterology
Understanding the potential impact of medications during pregnancy on fetal development is critical for ensuring medication safety and promoting optimal neurodevelopmental outcomes throughout life. Read more
 Supervisors: Dr BB Bano-Otalora, Dr G. Morris, Dr RB Bromley
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Mechanistic and Translational Studies of RNUopathies, Highly Prevalent Neurological Disorders Caused by Variants in Non-coding Genes

The University of Manchester
Division of Evolution, Infection and Genomics
We are looking for a highly motivated candidate wishing to tackle important translational research questions at the interface of genomics, stem cell biology and neuroscience. Read more
 Supervisors: Prof S Banka, Dr AJ Jackson, Prof S Kimber, Dr G. Morris
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Early-Stage Detection of Alzheimer’s and Parkinson’s Disease using Advanced Retinal Imaging Technology

The University of Manchester
Division of Pharmacy and Optometry
We are seeking a PhD student for an investigation using advanced retinal imaging technology and machine learning to develop a sensitive and specific diagnostic test for Alzheimer’s disease and Parkinson’s disease. Read more
 Supervisors: Dr KH Hampson, Prof T Aslam, Dr R Dune
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Undiagnosed Psoriatic Arthritis Across the Lifecourse: Early Warning Signs

The University of Manchester
Division of Musculoskeletal and Dermatological Sciences
There is often significant delay to diagnosis for children and adults with psoriatic arthritis. In children, arthritis often precedes psoriasis, leading to incorrect diagnoses of oligoarticular or polyarticular juvenile idiopathic arthritis. Read more
 Supervisors: Dr S Shoop-Worrall, Dr J Bowes, Dr James Bluett, Dr M Yates
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Investigating a neurodevelopmental disorder caused by defects in the protein synthesis machinery

The University of Manchester
Division of Molecular and Cellular Function
  Research Group: Division of Molecular and Cellular Function
Explore human neurodevelopment while advancing modern biomedical science in this innovative PhD project. Join a dynamic interdisciplinary team investigating how rare mutations in the protein synthesis machinery cause a complex neurodevelopmental disorder. Read more
 Supervisors: Prof G D Pavitt, Dr P Kasher, Prof S Banka
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Preserving sight in retinitis pigmentosa: why do cone cells die?

The University of Manchester
Division of Neuroscience
  Research Group: Division of Neuroscience
Retinitis pigmentosa (RP) is an inherited eye disease that causes progressive and irreversible vision loss. It affects around f 1 in 3,000 people and is a major cause of blindness across the lifespan. Read more
 Supervisors: Dr A Allen, Dr Nina Milosavljevic, Dr PS Sergouniotis
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Improving health professional communication regarding the risk and symptoms of infant Group B Streptococcus infections during the perinatal period

The University of Manchester
Division of Psychology and Mental Health
Group B Streptococcus (GBS) is a common bacterium that can cause sepsis, meningitis and other serious illness in babies. Early treatment is vital, yet symptoms can resemble typical newborn behaviour. Read more
 Supervisors: Dr S Lyons, Dr S Peters, Dr T Smith
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Genetic Variation in Circadian Pathways and its Role in Osteoarthritis Susceptibility

The University of Manchester
Division of Musculoskeletal and Dermatological Sciences
  Research Group: Division of Musculoskeletal and Dermatological Sciences
Osteoarthritis (OA) is a complex disease affecting 300 million people. Despite its prevalence, there are currently no molecular biomarkers or effective disease-modifying treatments. Read more
 Supervisors: Dr G Orozco, Prof Q-J Meng, Ms L Biant, Prof S Eyre
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Mapping the immune-matrix microenvironment in metastatic ovarian cancer

The University of Manchester
Division of Cell Matrix Biology and Regenerative Medicine
  Research Group: Division of Cell Matrix Biology and Regenerative Medicine
High-grade serous ovarian cancer (HGSOC) is the most aggressive ovarian cancer subtype, and metastasis within the peritoneal cavity leads to resistance to therapy and poor patient outcomes. Read more
 Supervisors: Dr P Caswell, Dr R Morgan, Mr M Nobis, Prof R Edmondson
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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