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PhD Projects, Programmes & Scholarships

We have 3,172 PhD Projects, Programmes & Scholarships

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Scalable and Interpretable Time Series Machine Learning for Industrial Systems

Modern manufacturing, engineering and automotive systems generate vast volumes of time series data at high speed. Read more
 Supervisors: Dr MB Middlehurst, Prof S Konur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Evaluating the genetic basis and evolution of virulence and antimicrobial drug resistance in Helicobacter pylori in a populational model

Project background. Characterization of the genetic variation of bacterial species and the evolutionary mechanisms leading to that variation is crucial for understanding bacterial adaptation to their host environments, as well as the evolution of phenotypes such as virulence and antimicrobial drug resistance (AMR). Read more
 Supervisors: Dr S Beleza, Dr K Schilcher, Dr FF Freund
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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AI for Understanding and Safeguarding Online Social Networks: Mapping Dynamics and Countering Threats

Online social networks have become central to how people share news, form opinions, and connect with communities, shaping both social behaviour and public perception on a global scale. Read more
 Supervisors: Dr A Zareie, Prof S Konur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Non-tuberculous mycobacteria in agrifood and the environment at the human-animal-ecosystems interface: resistance, persistence and longevity

Second Supervisor. Dr Marie Kirby, Agriculture and Environment, Harper Adams University. Project Outline. Environmentally resident mycobacteria are important animal pathogens known to infect cattle, pigs, fowl, sheep and most other commercially valuable livestock. Read more
 Supervisor: Dr J Pearl
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of a Patient-Specific Corneal Digital Twin Based on Topographic Imaging for Contact Lens Fitting and Future Corneal Interventions

This PhD project aims to develop a patient-specific corneal digital twin derived exclusively from routinely acquired corneal topography and tomography data. Read more
 Supervisors: Prof R Qahwaji, Dr I Ghafir
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring Weather Events Affecting The Health and Emergency intensive care admissions of children using Routine data: the WEATHER study

Background. Climate change and air pollution pose a significant global challenge, disproportionately affecting the health and lives of children.1 Despite lifelong exposure, little is known about how weather impacts children, even though air pollution, which is closely linked with weather, harms every organ in the body. Read more
 Supervisors: Dr S.E. Seaton, Prof J Manning, Dr TL Lucas
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mapping cardiac microstructure in aortic stenosis and diabetes using diffusion MRI and machine learning

Heart failure remains one of the leading causes of hospitalisation and death worldwide. Two of its most important causes, type 2 diabetes and aortic stenosis, both lead to thickening and stiffening of the heart muscle, but the microscopic processes underlying these changes are not fully understood. Read more
 Supervisors: Dr M Afzali, Prof G McCann, Dr A Singh, Dr TP Pearce
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Aldehyde dehydrogenase expression and function in cancer stem cells

Aldehyde dehydrogenases (ALDHs) catalyse the oxidation and detoxification of reactive endogenous and exogenous aldehydes into carboxylic acids via NAD+ coupled reduction. Read more
 Supervisors: Prof K Pors, Dr S Swaroop, Dr A Ruiz Estrada
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more
 Supervisors: Prof K Pors, Dr V Jha, Dr Muhammad Wahajuddin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Our agricultural future: Crop genomics, biodiversity and phylogenetics in the context of evolution of genome organization, epigenetics, and phylogenetics

At the forefront of agricultural genetics, the fundamental objectives of the project aim to define biodiversity and relationships of agricultural species and their wild relatives, leading to prospects for developing new genotypes and approaches to increase farm sustainability and ensure food security. Read more
 Supervisor: Prof P HESLOP-HARRISON
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of antibody-drug conjugates (ADCs) for oncology indications

A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more
 Supervisors: Prof K Pors, Dr Muhammad Wahajuddin, Prof R Falconer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Consequences of CD20 ligation in diffuse large B cell lymphoma

The addition of the monospecific chimeric CD20 antibody rituximab to chemotherapy transformed outcomes for patients with DLBCL without additional significant toxicities (1). Read more
 Supervisors: Dr H Walter, Dr Y Markaki, Prof M J S Dyer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only