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PhD Projects, Programmes & Scholarships

We have 3,174 PhD Projects, Programmes & Scholarships

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Peptide-like hydrogels as a long-acting injectable delivery technology for the treatment of ocular disease

Provide a brief description of the project. Rationale. There is a significant need for innovative treatments to alleviate the burden of macular disease. Read more
 Supervisors: Dr G Laverty, Prof R Thakur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of general practice pharmacists in supporting medicines use by people living with dementia

Medicines are a cornerstone of chronic disease management, including for people living with dementia (PLWD), who frequently experience polypharmacy and complex medication regimens. Read more
 Supervisors: Dr H Barry, Prof C Hughes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Microneedle-mediated Intradermal Delivery: Potential for Lymphatic Targeting of Therapeutic Agents

Though immunotherapy has revolutionized the treatment of cancer to improve disease outcomes, an array of challenges remain that limit wider clinical success, including low rate of response and immune-related adverse events. Read more
 Supervisors: Prof R Donnelly, Dr A Paredes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Modulating the Gut Microbiome to Reduce Infection Risk

Infection development, including surgical site infections (SSI) and urinary tract infections (UTI), remains a major cause of morbidity, prolonged hospital stay, and antimicrobial use. Read more
 Supervisors: Dr S Kelly, Dr T Skvortsov
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Novel, rheologically-structured implants for the prevention/treatment of bovine mastitis

Bovine mastitis has already been recognized as one of the most serious problems that affects milk production and quality, resulting in large financial losses to dairy farmers. Read more
 Supervisors: Prof D Jones, Prof G Andrews
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cutting to the Core: Mechanistic Dissection of Nuclear Protease Function in Tumour Biology

Proteases are classically viewed as degradative enzymes that function in the cytoplasm or extracellular space. Emerging evidence reveals a surprising role for specific proteases within the nucleus, where they influence key processes such as chromatin remodelling, transcriptional control, and DNA repair. Read more
 Supervisors: Dr R Burden, Dr J Burrows
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of Nano-Liposome Based Drug Delivery Systems for Ocular Diseases

Ocular drug delivery presents one of the greatest challenges in pharmaceutical science, largely due to the eye’s unique anatomy, which limits drug permeation to the intended site of action. Read more
 Supervisors: Prof R Thakur, Dr LV Vora
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design and Assessment of Innovative Long-Acting Drug Delivery System

Current clinical therapies often rely on intermittent drug administration, such as frequent oral tablets or injections, as seen in diabetes management. Read more
 Supervisors: Prof R Thakur, Prof D Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development and Evaluation of Microneedle Arrays for Ocular Drug Delivery

Minimally invasive microneedles (MNs) offer unique opportunities to address current challenges in the effective management of ocular disorders, such as age-related macular degeneration and diabetic retinopathy. Read more
 Supervisors: Prof R Thakur, Prof R Donnelly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of Peptide-Based Nanomicelle Eye Drops for the Treatment of Dry Eye Disease

Ocular drug delivery remains a major challenge due to the eye’s complex anatomy and dynamic protective barriers that restrict drug absorption. Read more
 Supervisors: Prof R Thakur, Prof D Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Computational and Functional Comprehensive Analysis of Natural Variants of GPCRs towards a personalized medicine approach

This project investigates the impact of natural genetic variations on a specific G protein-coupled receptor (GPCR), focusing on its structure, function, and drug interactions. Read more
 Supervisors: Dr I Tikhonova, Dr B Plouffe
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Implants for Localised Combination Therapy in Cancer: Delivery of Anticancer Drugs and Radiosensitisers

This PhD project will develop biodegradable implants for the localised treatment of solid tumours using combination therapy. The implants will be primarily fabricated using melt-processing techniques, enabling scalable and reproducible production of drug-loaded devices. Read more
 Supervisors: Dr E Larraneta, Dr J Coulter
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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3D-Printed Biodegradable Implants for Localised Anti-inflammatory Drug Delivery in Arthritis.

This PhD project will develop advanced biodegradable implants for the localised and sustained delivery of anti-inflammatory drugs to treat arthritis. Read more
 Supervisors: Dr E Larraneta, Prof R Donnelly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of Chemoresistance in high grade serous ovarian cancer

High-grade serous ovarian cancer (HGSOC) is the most aggressive form of epithelial ovarian cancer and is typically diagnosed at an advanced stage. Read more
 Supervisors: Dr F Furlong, Dr J Coulter
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Combination Drug Screening to Identify Novel Therapeutic Strategies for Rare Ovarian Cancers

Rare ovarian cancers represent a diverse group of malignancies that account for a small proportion of ovarian cancer diagnoses but contribute disproportionately to treatment failure and poor outcomes. Read more
 Supervisors: Dr F Furlong, Dr N Buckley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only