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PhD Projects, Programmes & Scholarships

We have 3,359 PhD Projects, Programmes & Scholarships

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The macromolecular basis of nuclear remodelling in humans

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
Our lab focuses on understanding the processes which lead to a reshaping of the nuclear compartment in health and disease. The nucleus is continuously reshaped by the cytoskeletal filaments that surround it. Read more
 Supervisor: Dr M Allegretti
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigating how water-rock interactions influence geothermal reservoir sustainability using experiments and geochemical modelling

Newcastle University
School of Natural and Environmental Sciences
Award summary. 100% home fees covered, and a minimum tax-free annual living allowance of £21,805 (2026/27 UKRI rate). An additional allowance will be provided to contribute towards consumables, equipment, and travel related to the project. Read more
 Supervisor: Dr S Acikalin
 2 October 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Structures and mechanisms of the human replisome

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
Accurate genome duplication is essential for all forms of life. Read more
 Supervisor: Dr J Yeeles
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Closing the loops: Unleashing the poteintial mTORC2.

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
mTORC2 can integrate multiple activating influences to positively influence anabolism, survival and cytoskeletal remodelling. We have characterised a positive feedback loop between mTORC2 and AKT and have shown that mTORC2 has a great potential for activation that has been overlooked in previous work. Read more
 Supervisor: Dr R Williams
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Non-protein ubiquitylation in infection and physiology

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
Ubiquitylation is essential for eukaryotic life. Until recently, proteins were the only substrates known to be modified with ubiquitin. Read more
 Supervisor: Dr F Randow
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Gatekeepers of GPCR Signalling: Degradation Pathways in Health and Diseas

University of Bristol
School of Biochemistry and Biomedical Sciences
G protein-coupled receptors (GPCRs) are the largest family of cellsurface signalling proteins and mediate communication between cells throughout the body and brain. Read more
 Supervisors: Dr A Grieve, Prof I Collinson
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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The life cycle of ecDNA

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
A major focus of the lab is understanding the links between replication and mutagenesis (1‑4). Extrachromosomal DNA (ecDNA) circles are present in a substantial proportion of cancers and frequently harbour oncogenes that drive tumour proliferation (5). Read more
 Supervisor: Dr J Sale
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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TRIM21 degradation of viruses and aggregates

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
TRIM21 is the cytosolic E3 ligase and antibody receptor responsible for intracellular antibody immunity. Unlike other ubiquitin ligases, TRIM21 doesn’t have a defined substrate but is directed towards its targets by antibodies. Read more
 Supervisor: Dr L James
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigating cellular mechanisms of tissue homeostatis and fibrosis using omics approaches

University of Southampton
School of Biological Sciences
Understanding how cells maintain tissue health or trigger irreversible decline is a frontier challenge in biomedical science. Using lung fibrosis as a primary disease model, this project investigates the core molecular networks controlling cellular fate, tissue regeneration, and scarring. Read more
 Supervisors: Dr K N Natarajan, Dr M Jones
 18 October 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Replicating RNA with RNA

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
A critical event in the origin of life is thought to have been the emergence of an RNA molecule capable of self-replication as well as mutation, and hence evolution towards ever more efficient replication. Read more
 Supervisor: Dr P Holliger
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Circuit basis of learning and action-selection

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
The overall goal of our research is to discover the circuit implementation of learning and action selection. Read more
 Supervisor: Dr M Zlatic
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Transforming Thoughts into Actions

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
How does the brain transform what we perceive into what we do? Even a simple action, such as stopping at a red light and moving again when it turns green, requires the brain to select relevant sensory information, form an intention, prepare an appropriate movement and execute it at the right moment. Read more
 Supervisor: Dr M Tripodi
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Neuropeptide networks in worms and octopus

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
In recent years, great efforts have been made to map the synaptic wiring diagrams of simple and complex nervous systems. However, chemical synapses, the connections used in most connectomics research, represent only one type of functionally important signalling between neurons. Read more
 Supervisor: Dr W Schafer
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Pathological protein assembly in neurodegenerative diseases

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
Neurodegenerative diseases are one of the greatest health challenges facing our society. This large group of diseases is characterised by the pathological assembly of specific proteins into amyloid filaments in the central nervous system. Read more
 Supervisor: Dr B Falcon
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Connectomics across sexes, species and states

Medical Research Council (Cambridge)
Laboratory of Molecular Biology
Neuroscience in the fly and beyond is being transformed by the availability of connectomes, synaptic resolution wiring diagrams. We have played leading roles in two large collaborations that have recently generated and analysed separate (female) brain and (male) nerve cord connectomes for the fly. Read more
 Supervisor: Dr G Jefferis
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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