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PhD Projects, Programmes & Scholarships

We have 3,658 PhD Projects, Programmes & Scholarships

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How do transcriptional kinases regulate cell cycle progression?

Project. Cyclin-dependent kinases (CDKs) are protein kinases performing essential functions by regulating cell cycle and RNA polymerase II transcription of protein-coding and non-coding genes. Read more
 Supervisors: Dr MT Tellier, Dr R Mahen
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of galectins in oncogenic KRAS signalling

Background. The RAS family of small GTPases serves as signalling hubs that regulate cell proliferation and differentiation. Notably, approximately 18% of all human cancers contain mutations in KRAS, one of the RAS isoforms (Catalogue Of Somatic Mutations In Cancer (COSMIC)). Read more
 Supervisors: Dr K Tanaka , Prof BG Gooptu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular characterization of suicidal phage-resistance mechanisms in bacteria

Importance. The proliferation of antibiotic resistance (AMR) through horizontal-gene-transfer (HGT) is a formidable health challenge, accounting for 700,000 deaths annually1. Read more
 Supervisors: Dr A Koyamangalath Vadakkepat , Dr M Clokie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Multimodal Assessment of Falls Risk/ Movement Performance in Older Adults Using Wearable Sensor Technologies and Visual Computing Techniques

Falls are a leading cause of severe injury and loss of functional independence among older adults. Performance measures derived from gait and postural assessments offer valuable insight into an individual’s movement quality (and hence their falls risk). Read more
 Supervisors: Dr J Buckley, Prof R Qahwaji, Dr R Jaber
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Why do we get sick when we are stressed?

Hypothesis. We hypothesise that host stress, via catecholamine stress hormones (norepinephrine, epinephrine, dopamine), plays a critical role in triggering the transition of Streptococcus pneumoniae from a benign coloniser in the nasopharynx to an invasive pathogen. Read more
 Supervisors: Dr H Yesilkaya, Dr L Cuthbertson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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AI-based dementia screening using emotion change detection in speech signals

With the development of AI tools, including machine/deep learning, speech signal processing has reached a high level of accuracy, both for neutral and expressive speech. Read more
 Supervisors: Dr Z Mnasri, Prof S Konur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural insights into how Mycobacterium tuberculosis interacts with human cells

Project. Mycobacterium tuberculosis is the leading global cause of death from a single infectious agent. It is a highly specialised human pathogen and is able to adapt to changing conditions in human macrophages and granulomas in order to subvert immune defences. Read more
 Supervisors: Dr H O'Hare, Dr AKV Koyamangalath Vadakkepat
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bacteria, Phages, and Iron: Decoding the Molecular Tug-of-War in Microbial Ecosystems

Iron is an essential nutrient for virtually all life on Earth, playing a critical role in processes such as respiration, DNA synthesis, and metabolism (1). Read more
 Supervisors: Dr C Jenul, Dr A Millard
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bacterial lipid bodies: Targeting pathogen fat reserves for infection control

Bacterial lipid bodies (LBs), also known as intrabacterial lipid inclusions or lipid droplets, are intracellular accumulations of neutral lipids, such as triacylglycerol (TAG) and wax esters. Read more
 Supervisors: Dr N Garton, Prof G Mukamolova
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Scalable and Interpretable Time Series Machine Learning for Industrial Systems

Modern manufacturing, engineering and automotive systems generate vast volumes of time series data at high speed. Read more
 Supervisors: Dr MB Middlehurst, Prof S Konur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Evaluating the genetic basis and evolution of virulence and antimicrobial drug resistance in Helicobacter pylori in a populational model

Project background. Characterization of the genetic variation of bacterial species and the evolutionary mechanisms leading to that variation is crucial for understanding bacterial adaptation to their host environments, as well as the evolution of phenotypes such as virulence and antimicrobial drug resistance (AMR). Read more
 Supervisors: Dr S Beleza, Dr K Schilcher, Dr FF Freund
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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AI for Understanding and Safeguarding Online Social Networks: Mapping Dynamics and Countering Threats

Online social networks have become central to how people share news, form opinions, and connect with communities, shaping both social behaviour and public perception on a global scale. Read more
 Supervisors: Dr A Zareie, Prof S Konur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Non-tuberculous mycobacteria in agrifood and the environment at the human-animal-ecosystems interface: resistance, persistence and longevity

Second Supervisor. Dr Marie Kirby, Agriculture and Environment, Harper Adams University. Project Outline. Environmentally resident mycobacteria are important animal pathogens known to infect cattle, pigs, fowl, sheep and most other commercially valuable livestock. Read more
 Supervisor: Dr J Pearl
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of a Patient-Specific Corneal Digital Twin Based on Topographic Imaging for Contact Lens Fitting and Future Corneal Interventions

This PhD project aims to develop a patient-specific corneal digital twin derived exclusively from routinely acquired corneal topography and tomography data. Read more
 Supervisors: Prof R Qahwaji, Dr I Ghafir
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring Weather Events Affecting The Health and Emergency intensive care admissions of children using Routine data: the WEATHER study

Background. Climate change and air pollution pose a significant global challenge, disproportionately affecting the health and lives of children.1 Despite lifelong exposure, little is known about how weather impacts children, even though air pollution, which is closely linked with weather, harms every organ in the body. Read more
 Supervisors: Dr S.E. Seaton, Prof J Manning, Dr TL Lucas
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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