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PhD Projects, Programmes & Scholarships

We have 3,670 PhD Projects, Programmes & Scholarships

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Unmasking molecular pathways of sarcopenia and muscle dysfunction and their biomarkers

Sarcopenia is a disease that affects individuals both as part of the normal ageing process and as a consequence of systemic disease. Read more
 Supervisors: Dr H McAuley, Dr LAB Baker, Prof D Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Inference and Error Detection in Reading: Cognitive and Linguistic Mechanisms

Can you spot the grammatical error this in sentence? Many readers initially fail to detect small disruptions in a sentence, such as an omitted word, an unintended repetition, or a swap of adjacent words. Read more
 Supervisors: Dr K Warrington, Dr V McGowan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Improving meta-analysis of complex healthcare interventions: Application to chronic obstructive pulmonary disease

Health and social care interventions—like those for quitting smoking or managing weight—are often made up of several parts. For example, a smoking cessation programme might include motivational sessions, behaviour-change strategies, and different delivery formats (online, in-person, group sessions) [1]. Read more
 Supervisors: Dr S Freeman, Prof A Sutton, Dr ES Smith
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring Oxygenase Chemistry: Enzymatic Pathways to Novel Antibiotics

Nature uses a remarkable range of oxygenase enzymes to perform highly selective oxidation reactions—transformations that are often challenging or wasteful to achieve chemically. Read more
 Supervisors: Dr H Kwon, Prof A Hudson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Visualizing cellular control centres: Advanced imaging of centrosomes to understand disease

Project. Cells rely on tiny but essential structures called centrosomes, which act as control centres to organize their internal skeleton and guide cell division. Read more
 Supervisors: Dr R Mahen, Dr R Hirst
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How do transcriptional kinases regulate cell cycle progression?

Project. Cyclin-dependent kinases (CDKs) are protein kinases performing essential functions by regulating cell cycle and RNA polymerase II transcription of protein-coding and non-coding genes. Read more
 Supervisors: Dr MT Tellier, Dr R Mahen
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of galectins in oncogenic KRAS signalling

Background. The RAS family of small GTPases serves as signalling hubs that regulate cell proliferation and differentiation. Notably, approximately 18% of all human cancers contain mutations in KRAS, one of the RAS isoforms (Catalogue Of Somatic Mutations In Cancer (COSMIC)). Read more
 Supervisors: Dr K Tanaka , Prof BG Gooptu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular characterization of suicidal phage-resistance mechanisms in bacteria

Importance. The proliferation of antibiotic resistance (AMR) through horizontal-gene-transfer (HGT) is a formidable health challenge, accounting for 700,000 deaths annually1. Read more
 Supervisors: Dr A Koyamangalath Vadakkepat , Dr M Clokie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Multimodal Assessment of Falls Risk/ Movement Performance in Older Adults Using Wearable Sensor Technologies and Visual Computing Techniques

Falls are a leading cause of severe injury and loss of functional independence among older adults. Performance measures derived from gait and postural assessments offer valuable insight into an individual’s movement quality (and hence their falls risk). Read more
 Supervisors: Dr J Buckley, Prof R Qahwaji, Dr R Jaber
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Why do we get sick when we are stressed?

Hypothesis. We hypothesise that host stress, via catecholamine stress hormones (norepinephrine, epinephrine, dopamine), plays a critical role in triggering the transition of Streptococcus pneumoniae from a benign coloniser in the nasopharynx to an invasive pathogen. Read more
 Supervisors: Dr H Yesilkaya, Dr L Cuthbertson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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AI-based dementia screening using emotion change detection in speech signals

With the development of AI tools, including machine/deep learning, speech signal processing has reached a high level of accuracy, both for neutral and expressive speech. Read more
 Supervisors: Dr Z Mnasri, Prof S Konur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural insights into how Mycobacterium tuberculosis interacts with human cells

Project. Mycobacterium tuberculosis is the leading global cause of death from a single infectious agent. It is a highly specialised human pathogen and is able to adapt to changing conditions in human macrophages and granulomas in order to subvert immune defences. Read more
 Supervisors: Dr H O'Hare, Dr AKV Koyamangalath Vadakkepat
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bacteria, Phages, and Iron: Decoding the Molecular Tug-of-War in Microbial Ecosystems

Iron is an essential nutrient for virtually all life on Earth, playing a critical role in processes such as respiration, DNA synthesis, and metabolism (1). Read more
 Supervisors: Dr C Jenul, Dr A Millard
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bacterial lipid bodies: Targeting pathogen fat reserves for infection control

Bacterial lipid bodies (LBs), also known as intrabacterial lipid inclusions or lipid droplets, are intracellular accumulations of neutral lipids, such as triacylglycerol (TAG) and wax esters. Read more
 Supervisors: Dr N Garton, Prof G Mukamolova
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Scalable and Interpretable Time Series Machine Learning for Industrial Systems

Modern manufacturing, engineering and automotive systems generate vast volumes of time series data at high speed. Read more
 Supervisors: Dr MB Middlehurst, Prof S Konur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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